Diabetes Insipidus in Children,Symptoms ,Treatment & Diagnosis

Diabetes Insipidus in Children-Diabetes insipidus is a rare disease, and is associated with the violation of water and electrolyte balance in the system. The first symptoms of diabetes insipidus in children can occur at any age, depending on the type of pathology.

Diabetes Insipidus in Children
Diabetes Insipidus in Children

As diseases of the endocrine system, diabetes insipidus trigger excessive production of urine, but does not affect the level of glucose (sugar) in the blood. Types of disease developing on the failure of the Central background motion synthesis (transport) and release of antidiuretik hormone-vasopressin.

For its production meets the hypothalamus, and for storage-the neurohypophysis (posterior region of the pituitary gland). Its main task is to control the process of absorbing of return.
Isolation (secretion) hormones directly depend on the osmotic pressure of the liquid medium of the human body. If osmolaritas blood plasma vasopressin levels increase, increase, and vice versa.
Pediatric pathology can occur due to various reasons.

The main factors include:
• Brain Tumor
• Congenital pituitary and hypothalamus
• Infectious disease and viruses have been migrated (toxoplasmosis, SARS, a sore throat, influenza, pertussis, pneumonia)
• Skull injury (fracture, especially basis)
• The effect of neurological intervention
• Autoimmune, cardiovascular disease
Often the actual etiology of development can not know the endocrine disorders diabetes insipidus and.

In order to establish a diagnosis of the child need to repeatedly undergo a medical examination, as the first signs of abnormality appears not always after an injury or illness development.
On diabetes insipidus children associated with the lack of production of the hormone antidiuretik in the hypothalamus.

 Diagnosis of diabetes insipidus 


Diabetes Insipidus in Children
Diabetes Insipidus in Children

Can enforce a diagnosis the doctor after the examination. First of all, the physician who is interested in the young patient complaints. Find out how much fluid a patient drinking day and how much urine is released around. If the amount exceeds the value of 3 liters, the possibility of diabetes insipidus is substantially increased.

Symptoms of diabetes insipidus in children


Identify abnormalities in infants difficult. Parents should pay attention to the amount allocated in the urine within 24 hours and the amount of liquid is drunk. Toddlers can leave power, requiring only water.

Increased thirst cause urinary incontinence at night and during the day. The average amount of urine in children is 3-8 liters. The concentration and density will not correspond to the normal indicators.
In the development of the following symptoms of disease: children
• Becomes irritable and Moody
• There are signs of dehydration (headaches, weight loss, dry mucous membranes)
• Loss of appetite (due to the lower production of saliva and gastric juices)
• Develop the symptoms of gastritis, colitis
• Fever and constipation
• Interference
• Psychoemotional, irritability

Large quantities are consumed can cause fluid to blood pressure, tachycardia, anemia, abdominal wall distance and bladder. Some children complain of pain in the joints. Rarely left in the physical development, stunt, severe fatigue.

With the rise of child is drinking lots of water each time. So for a pee can stand up to 600 ml. Reduce the concentration affects color, so light and airy, which is not typical for a healthy baby.

Should be careful to take care of the appearance of symptoms of diabetes insipidus in children. You don't have to drastically reduce the amount of water in the diet, or completely stop the baby water. This can lead to signs of more severe seizures, unconsciousness, death.
Should immediately seek medical help to find symptoms of the disease in children.

Renal diabetes insipidus


Nephrogenic diabetes – a kind of Pathology associated with congenital abnormalities. In this case, the level of vasopressin is stored in a normal, but kidney receptor sensitivity to disturbance. The kidneys stop emitting a low concentration of urine osmolalitas. Impaired renal function homeostatis.

In the more likely for a boy who proved the disease nephrogenic diabetes hereditary. In girls, the symptoms are rarely disclosed in full, and mostly limited to signs poliuria. Children refuse liquids, and water that is trapped in the body often leads to vomiting. nephrogenic diabetes first symptoms in children occur at age 3-6 months.

POPs released large amounts of vomiting, urine (about 4 liters) per day, the fever. The feeling of thirst in children may be missing that eventually leads to violation of chairs, sleep disorders. Fluid and electrolyte imbalance is a serious threat to the normal development of children continues. The country is rife with development of malnutrition, retarded mental and physical development.

Renal diabetes insipidus is almost always obtained. With such leading pathology hiperkalsemia, kidney stones, Ureteral occlusion Polycystic, hypokalemia, kidney failure. Excessive fluid intake causes elusi gradients responsible for concentration of the urine. Help diagnose disease and microdissection of biopsy of the kidney tubules.
Renal diabetes insipidus can be hereditary or other disease pathology results.

Treatment


For the successful treatment have to pass a comprehensive exam and to identify the etiology of the disease. Symptoms of diabetes insipidus is not going to bother children in terms of the underlying pathology medicine. For each patient, doctors choose individual courses of medical action. 

If there is enough Vasopressin, the hormone antidiuretik produced by the pituitary gland, prescribe replacement therapy with synthetic analog. This helps to reduce the amount of urine daily, improve density. drug therapy can be received when the volume of urine per day from 4 liters.

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