Insulin Glargine-Definitions,Dose, Functions, Etc.

Insulin glargine for what?

Insulin glargine is a drug that is commonly used with a proper diet and physical exercise to control blood sugar levels. The drug is intended for type 1 diabetes patients(with insulin dependent) and type 2 diabetic patients. This drug is a man-made drug that its shape is similar to that of human insulin. This medication works faster and does not last long as regular insulin.

Insulin Glargine 

Insulin is a natural substances that allow the body to use sugar in your daily diet. The drug is replacing the insulin your body that is no longer manufactured, so that it can lower your blood sugar. Controlling high blood sugar can help prevent kidney damage, blindness, nerve problems, loss of limbs, and the problems of sexual function.The right diabetic control can also reduce the risk of heart attack or stroke.

How do I use of glargine insulin?

Follow the rules that are listed on the packaging about the use of/injection/storage of multiple devices/medications you use. The nurse will tell you the correct way to inject this medication. If there are instructions and information that is unclear, please contact Your doctor or pharmacist.

Do not inject this medicine in a State of cold because it would be a pain. A place to put this medication should be stored at room temperature (see rules). Wash your hands before you take and inject this medication. Prior to treatment, please check your product to see if there is any foreign substance or discoloration. If one of these two things exist, do not use this medication. This medication should be clear and colorless. To avoid damage, do not shake the bottle storage of medicines.

The dosage of these drugs can be determined based on Your medical condition and response of the body's response to treatment. Arrange the dosage carefully because only a dose change may affect your blood sugar levels. If you use other tools in the cartridge or injecting drugs, point on-screen pointer towards the top so you can clearly see, if you direct the pointer down the screen, there is a chance you take the number of injections of the drug. Ask Your pharmacist if you are unsure about the use of tools.

Before starting treatment, make sure the syringes are clean and dry. Inject drugs on the skin area of the abdomen, upper arm, or thigh once a day or according to your doctor's advice. Don't these drug injections in the area of blood vessels or muscles.Replace syringe every you are done in order to reduce the cuts under the skin area and to avoid problems under the skin that may arise.

Use this medication regularly in order to get optimal benefits. You can inject these drugs just once a day and can be done at any time (e.g. Before breakfast or before going to bed). Keep in mind, you have to inject this medication at the same time every day. Follow carefully all the treatment plan, plans food intake, and physical exercise plan already advised your doctor.

Do not mix this medication with other insulin, unless you use an insulin pump.

Regularly monitor your blood sugar levels. It is very important for the doctor can determine the dose of insulin. Notify your doctor if your blood sugar level is too high or too low, so your doctor may change the dose of the drug.

If you take the dosage using a small bottle, do not use a needle or the injection of more. If you are using the catridge or ampules, make sure to replace jarumnya any time completed. Consult your pharmacist if you need any other information.

How does insulin glargine storage?

Insulin Glargine 

Store the unopened bottles of medication in the refrigerator. Do not allow to freeze;and do not ever use drugs that are frozen and then thawed. Drugs that have not been opened and stored in the refrigerator can hold up until the expiration date indicated on the packaging.

If you do not currently have a refrigerator/cooler (for example when being a holiday), store the vials, cartridge, and ampules at room temperature and keep away from direct sunlight or high heat. Bottles, cartridges, and ampules are not stored in the fridge can be used for 28 days and after that it must be discarded. Ampules are already opened can be stored at room temperature for up to 28 days after the first usage. Dispose of medicines that are already exposed to hot or cold weather.

Each brand has a different way of storage. Check the box to see the storage instructions or ask Your pharmacist. Keep your medication out of reach of children and pets.

Do not flush medications into the toilet or down the drain unless instructed. Dispose of this product when the validity period had expired or when it is not needed anymore. To consult a pharmacist or local waste disposal company about how to safely dispose of your product.

 Dose 

The information provided is not a substitute for medical advice from. ALWAYS consult a doctor or pharmacist before starting treatment.

How dose of insulin glargine for adults?

General adult doses for type 1 Diabetes

Total daily insulin needs:

Initial dose: subcutaneous injection 0.5 – 0.8 units/kg/day

Phases of remission: subcutaneous injection of 0.2 – 0.5 units/kg/day

Separate doses of therapy: subcutaneous injection 0.5 – 1.2 units/kg/day

Subcutaneous injection of insulin resistance: 0.7 – 2.5 units/kg/day

General adult doses for type 2 Diabetes

Initial dose, subcutaneous injection monoterapi: 0.5 – 1.5 units/kg/day

Doses of treatment, monoterapi: the number of daily insulin requirements may be increased up to 2.5 units/kg or higher in patients of obesity and insulin resistance.

How dose of insulin glargine for kids?

Common dosage for type 1 Diabetes

> 6 years

Initial dose: subcutaneous injection 0.5 – 0.8 units/kg/day

Phases of remission: subcutaneous injection of 0.2 – 0.5 units/kg/day

Separate doses of subcutaneous injection therapy: 0.5-1.2 units/kg/day

Teen growth: during the height of the subcutaneous injection of 0.8-1.5 units/kg/day

The General dosage children for type 2 Diabetes

Initial dose, subcutaneous injection monoterapi: 0.5 – 1.5 units/kg/day

Doses of treatment, monoterapi: the number of daily insulin requirements may be increased up to 2.5 units/kg or higher in patients of obesity and insulin resistance.

In doses of insulin glargine are available?

Subcutaneous injection: 100 units/mL.

Side Effects

What side effects can be experienced due to insulin glargine?

The side effects include pain, redness, swelling, or itching after injecting. These side effects may disappear after a few days or weeks. If side effects worsen, contact Your doctor or pharmacist.

Remember that your doctor has prescribe drugs because he has argued that its benefits outweigh the risks or side effects. Most people using this medication do not have serious side effects.

Too much insulin can cause low blood sugar (hypoglycemia). This can also happen if you are not consuming enough calories. The symptoms that appear include chills, cold sweat, blurred vision, dizziness, drowsiness, shaking, rapid heart rate, weakness, headache, fainting, tingling of hands/feet, or hunger. Make it a habit to carry glucose (sugar) tablets to treat low blood sugar. If you do not have the form of glucose, you can quickly increase your blood sugar by eating food containing sugar such as sugar, honey, or candy, fruit juice or non-diet soda. Tell your doctor immediately about the reaction that you can. To help prevent low blood sugar, eat with a regular schedule and do not skip meals.

Too little insulin can lead to high blood sugar (hyperglycemia). High blood sugar symptoms including thirst, frequent urination, confusion, drowsiness, flushed face, breath fast, or the smell of your breath smells like fruit. If these symptoms occur, tell your doctor immediately. Your treatment plan may need to be modified.

This medicine can cause low potassium levels in the blood (hypokalemia). notify your doctor immediately if there is a possibility of side effects did not appear serious: muscle cramps, fatigue, irregular heart rate.

A very serious allergic reaction against this drug is rare. However, seek medical help immediately if you experience any of the following serious allergic reaction: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Not all people experience this side effect. There may be some side effects that are not mentioned above. If you have concerns about specific side effects, consultation on Your doctor or pharmacist.

Prevention & Warning

Insulin Glargine 

What should know before using insulin glargine?

Before starting treatment, you should:

• Tell your doctor and pharmacist if you are allergic to insulin (Humulin, Novolin, other), one of the ingredients of this medication, or against other drugs. Ask your pharmacist or check out the patient information brochure to view a list of product composition

• Tell your doctor if you are or have experienced nerve damage caused by diabetes; heart failure; or if you have other health conditions, including heart, kidney, or liver disease

• Call your doctor if you are pregnant, plan to become pregnant, or breastfeeding. If you become pregnant while using this drug, contact your doctor

• If you are having surgery, including dental surgery, tell the doctor or dentist that you are using this medicine

• Alcohol may cause changes in blood sugar. Ask your doctor about the safe use of if you drink alcoholic beverages while you are using insulin glargine

• Ask your doctor what to do if you are ill, experiencing unusual stress, or change the pattern of diet, exercise, or schedule your activities. This change may affect dosing schedules and the amount of insulin You

• Ask your doctor about how often you should check your blood sugar. Understand that hypoglycemia can affect your ability to perform activities such as driving. And ask your doctor if you need to check your blood sugar before driving or operating machinery

Whether insulin glargine is safe for pregnant and nursing mothers?

There are no adequate studies on the risk of the use of these drugs on pregnant or lactating women. Always consult a physician to consider the potential benefits and risks before using this medication. This remedy is the pregnancy risk category C according to the Food and Drug Administration (FDA).

The following references to the pregnancy risk category,according to the FDA:

• A = no risk

• B = no risk in several studies

• C = there may be some risk

• D = positive evidence of risk

• X = contraindications

• N = unknown

There has not been sufficient information about the safety of using this medicine during pregnancy and breastfeeding. Always consult Your physician to consider the potential benefits and risks before using this medication.

Interaction

What medications may interact with insulin glargine?

Drug interactions can alter the performance of your medication or increase the risk of serious side effects. Not all possible drug interactions are listed in this document. Save the list of all the products that you use (including prescription medicines/herbal products and nonresep) and consult a doctor or pharmacist. Do not start, stop, or change the dosage of any medication without a doctor's approval.

• Balofloxacin

• Besifloxacin

• Ciprofloxacin

• Dulaglutide

• Enoxacin

• Fleroxacin

• Flumequine

• Gatifloxacin

• Gemifloxacin

• Levofloxacin

• Lomefloxacin

• Metreleptin

• Moxifloxacin

• Nadifloxacin

• Norfloxacin

• Ofloxacin

• Pazufloxacin

• Pefloxacin

• Prulifloxacin

• Rufloxacin

• Sparfloxacin

• Tosufloxacin

The use of this drug in conjunction with one of the following medicines can cause an increased risk of side effects, but if you use the second oba simultaneously, may be able to give you the best results for you. If these two drugs are prescribed together, then your doctor may change the dose of either or both of your medication.

• Iproniazid

• Isocarboxazid

• Linezolid

• Methylene Blue

• Moclobemide

• Nialamide

• Phenelzine

• Procarbazine

• Rasagiline

• Selegiline

• Tranylcypromine

 

Whether food or alcohol can interact with insulin glargine?

Certain medicines should not be used when eating or eating certain foods because of drug interactions may occur. Consuming alcohol or tobacco with certain drugs can also cause the interaction to occur. Discuss Your use of medications with food, alcohol, or tobacco with your health care provider.

What health conditions that can interact with insulin glargine?

Other health conditions you have could affect the use of these drugs. Always tell the doctor if you have any other medical problems, especially:

• Emotional shocks

• Infection or other diseases

• Stress (for example, physical or emotional) – can increase blood sugar and can increase the number of aspart insulin you need

• Kidney disease

• Liver disease – side effects of these drugs can increase, because the process of cleaning the rest of the drugs from the body more slowly

Overdose

What should I do in a State of emergency or an overdose?

In the case of emergency or overdose, call your local emergency service providers (112) or immediately to the emergency unit of a nearby hospital. Overdose may occur if you use too much of this medication, or if you are using this medication in the right amount but you eat less or not exercising. An overdose of this drug can cause hypoglycemia. If you are experiencing symptoms of hipoglikimia, follow the doctor's orders that you provide. Other overdose symptoms are as follows:

• Lost consciousness

• Seizures

What should I do if a dose is missed?

Before you begin treatment, ask Your doctor what to do if you forget a dose. Write down all instructions so you can refer to your doctor later.

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